Intra-arterial thrombolysis agents following endovascular thrombectomy for acute ischemic stroke: a network meta-analysis.

Front Pharmacol · 2026 · PMC13370159 · PMID 42460018

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

reached borderline significanceno p-value reported

EVT + 0.0625 mg/kg TNK reached borderline significance, likely reflecting increased statistical power from pooling three underpowered direct-comparison studies ( Huang et al., 2025 ; Hu et al., 2025 ; Hou et al., 2025 ).

also in 370 other papers

did not reach statistical significanceno p-value reported

For functional independence (mRS 0–2) and favorable outcome (mRS 0–3), both EVT + 0.225 mg/kg ALT and EVT + 0.0625 mg/kg TNK maintained directionally favorable effects relative to EVT alone, although the differences did not reach statistical significance.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.