Effects of Exercise Type and Sertraline on Anxiety and Social Behavior in a Female Rat Model of PTSD.

Brain Behav · 2026 · PMC13396889 · PMID 42494175

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.1070

boldest claim

The sentences

highly significantp < 0.001actually significant

The analysis revealed a significant main effect of Sertraline treatment ( F (1, 24) = 54.219, p < 0.001) and a highly significant Interaction between Exercise and Sertraline ( F (2, 24) = 21.436, p < 0.001).

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did not reach statistical significancep = 0.107not close (p > 0.1)

However, the main effect of Sertraline treatment alone did not reach statistical significance ( F (1, 24) = 2.798, p = 0.107).

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a negative trendno p-value reported

While a negative trend was initially observed between corticosterone and open arm time (OT), this association did not remain statistically significant after FDR correction ( r = −0.29, q = 0.128).

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