Bone-Targeted Therapies and Spinal Morphometry in Postmenopausal Osteoporosis: A Real-World Longitudinal Retrospective Study.

Bioengineering (Basel) · 2026 · PMC13405480 · PMID 42510467

Europe PMC DOI

hedged sentences

0.0940

closest p · 1.9× alpha

0.0990

boldest claim

The sentences

a nonsignificant trendp = 0.094so close (0.05 < p ≤ 0.1)

28.37 ± 2.53 mm, p = 0.043), whereas L5 anterior height showed only a nonsignificant trend toward a higher value in the anabolic group (29.12 ± 1.97 vs. 28.24 ± 3.80 mm, p = 0.094).

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did not reach statistical significancep = 0.099so close (0.05 < p ≤ 0.1)

PI tended to be lower in the anabolic group, although this difference did not reach statistical significance (45.88 ± 13.74° vs. 50.49 ± 10.69°, p = 0.099; SMD = −0.40).

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nominally significantno p-value reported

After adjustment for baseline lumbar BMD and baseline TLK, the anabolic therapy coefficient remained nominally significant but did not remain significant after FDR correction (β = 3.478, 95% CI 0.042 to 6.914, p = 0.047; FDR q = 0.111).

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