Coagulation and Inflammatory Responses After Tourniquet Release in Total Knee Arthroplasty: Association with Hemodynamic Instability.

J Clin Med · 2026 · PMC13412553 · PMID 42513301

Europe PMC DOI

hedged sentences

0.0970

closest p · 1.9× alpha

0.0970

boldest claim

The sentences

did not reach statistical significancep = 0.097so close (0.05 < p ≤ 0.1)

Cytokine Analysis ΔPeak IL-6 levels were higher in the hemodynamically unstable group compared to the stable group; however, this difference did not reach statistical significance (Mann–Whitney U = 21.5, Z = −1.662, p = 0.097).

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showed a trendno p-value reported

Although no definitive biomarker of hemodynamic instability was identified, ΔPeak IL-6 showed a trend toward association with instability and may merit further investigation.

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