However, this estimate did not reach statistical significance (OR 4.76, 95% CI 0.48–47.8), possibly due to the low number of subjects with all the three at-risk genotypes (four cases and one control).
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XRCC1 and XPD genetic polymorphisms, smoking and breast cancer risk in a Finnish case-control study.
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The sentences
Moreover, a significant trend of increasing risk with increasing number of the putative at-risk genotypes ( p for trend 0.042) was seen.