Modulation of T cell function by combination of epitope specific and low dose anticytokine therapy controls autoimmune arthritis.

Treatment with HSP60 peptide 180-188 alone showed a trend towards reduction of arthritis, without achievement of statistically significant differences (Day 23 p = 0.07, AUC p = 0.26 vs. no treatment).

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ILN were able to induce a good level of clinical amelioration ( Figure 5-B ), however differences with no treatment control group did not reach statistical significance ( Figure 5-A ).

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