Combination of psychotherapy and benzodiazepines versus either therapy alone for panic disorder: a systematic review.

BMC Psychiatry · 2007 · PMC1894782 · PMID 17501985

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0.0800

closest p · 1.6× alpha

0.1200

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The sentences

failed to reach statistical significanceP = 0.08so close (0.05 < p ≤ 0.1)

However the results in the present review failed to reach statistical significance in terms of response rate (RR = 0.62, 0.36 to 1.07, P = 0.08) or the secondary outcome representing global severity of panic attacks (SMD = -0.19, -0.59 to 0.22, P = 0.37).

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showed a trendP = 0.08so close (0.05 < p ≤ 0.1)

Long-term after treatment termination At either 12 [ 41 ] or 7 [ 20 ] months of naturalistic follow-up after treatment termination, the RR of response rate showed a trend in favour of psychotherapy alone over combination (RR = 0.62, 95%CI: 0.36 to 1.07; P = 0.08) (Figure 5 ).

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a weak trendP = 0.12not close (p > 0.1)

Long-term after treatment cessation In terms of response after 7 months after treatment cessation, a weak trend in favour of the combination therapy (RR = 2.31, 95% CI: 0.79 to 6.74, P = 0.12) in terms of response rates, and a statistically significant superiority of the combination in terms of global severity was observed.

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