As CD31 and podoplanin RNA were both greatly reduced in the MDAMB231 tumours, this may account for the fact that there was decrease in growth of the MDAMB231 tumours following Celecoxib, even though the increase in apoptosis failed to reach statistical significance.
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Cyclooxygenase-2 inhibition: effects on tumour growth, cell cycling and lymphangiogenesis in a xenograft model of breast cancer.
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The sentences
There was also an increase in apoptosis in the MDAMB231 cell line that did not reach statistical significance.