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Cyclooxygenase-2 inhibition: effects on tumour growth, cell cycling and lymphangiogenesis in a xenograft model of breast cancer.

Br J Cancer · 2007 · PMC2360050 · PMID 17285134

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As CD31 and podoplanin RNA were both greatly reduced in the MDAMB231 tumours, this may account for the fact that there was decrease in growth of the MDAMB231 tumours following Celecoxib, even though the increase in apoptosis failed to reach statistical significance.

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There was also an increase in apoptosis in the MDAMB231 cell line that did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.