High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis.

Moreover, trends for a correlated expression of RELA and BCL2L1 as well as CCND1 could be observed, but failed to reach statistical significance ( r 2 =0.1504, P >0.05 and r 2 =0.2468, P >0.05, respectively, Figure 3C ).

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Concerning tumour stage and nodal status, a strong trend towards higher cytoplasmic and nuclear RelA expression levels was observed for locally more advanced and nodal-positive tumours ( Table 1 ).

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