GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON.

Br J Cancer · 2003 · PMC2394309 · PMID 14520462

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0560

boldest claim

The sentences

highly significantP =0.0001actually significant

There was a good geographical colocalisation of both intrinsic markers with pimonidazole and a highly significant agreement in individual patients; correlation coefficients were 0.82 ( P =0.0001) for GLUT1 and 0.74 ( P <0.0001) for CAIX.

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near-significantP =0.056so close (0.05 < p ≤ 0.1)

However, there was a positive correlation between GLUT1 and Ki-67 (Spearman's correlation=0.294, P =0.018) and a near-significant correlation between CAIX and Ki-67 (Spearman's correlation=0.24, P =0.056).

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showed a trendno p-value reported

The hypoxia markers did not predict for local control or metastases-free survival although higher Ki-67 indices showed a trend towards local failure.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.