A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2.

PLoS Genet · 2008 · PMC2481282 · PMID 18648537

Europe PMC DOI

hedged sentences

0.0100

closest p · 0.2× alpha

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boldest claim

The sentences

only marginally significantP = 0.01–0actually significant

Interestingly there were three SNPs in GSN (rs10985196, rs7046030 and rs12683459), all highly correlated with pairwise r 2 values >0.90, which were highly significant (trend P<10 −6 ) in Sample Set 2 but only marginally significant in Sample Set 1 (trend P = 0.01–0.05).

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moderately significantP = 0.015actually significant

Association of a Group 1 SNP, rs2416806, was moderately significant in a combined analysis of three of their sample sets (P = 0.015).

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