Atorvastatin also reduced the PAI-1 levels, but the effect failed to reach statistical significance, probably because the study was short and patients showed considerable variation in their PAI-1 levels.
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Flexible initial dosing of atorvastatin based upon initial low-density lipoprotein cholesterol levels in type 2 diabetic patients.
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The sentences
PAI-1 tended to decrease in patients receiving atorvastatin, but this parameter change did not reach statistical significance.