Barely Significant
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Treating COPD with PDE 4 inhibitors.

Int J Chron Obstruct Pulmon Dis · 2007 · PMC2699952 · PMID 18268925

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In two of four pivotal phase III studies, the drug failed to reach statistical significance in FEV 1 change, the co-primary endpoint.

also in 6,035 other papers

In two of the four pivotal phase III trials, cilomilast did not reach statistical significance over the placebo.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.