A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.

PLoS Genet · 2009 · PMC2719869 · PMID 19680540

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did not reach statistical significanceno p-value reported

However, qRT-PCR analysis did not reach statistical significance suggesting FTO I367F may only be initiating a mild unfolded protein response.

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showed a trendno p-value reported

This was not observed in Fto I367F mice although homozygotes showed a trend to towards reduced food intake on both standard and high-fat diets.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.