Mycobacterium tuberculosis ecology in Venezuela: epidemiologic correlates of common spoligotypes and a large clonal cluster defined by MIRU-VNTR-24.

BMC Infect Dis · 2009 · PMC2739208 · PMID 19660112

Europe PMC DOI

hedged sentences

0.0770

closest p · 1.5× alpha

0.1400

boldest claim

The sentences

did not quite reach statistical significancep = 0.077so close (0.05 < p ≤ 0.1)

The SIT 17 patients also had lower mean ages when the comparisons were stratified for each of the three regions with the most isolates, but the differences did not quite reach statistical significance (Caracas 35 vs 38.4, p = 0.077; Carabobo 34.5 vs 39.8 p = 0.076; and Amazonas 30.6 vs 39.1, p = 0.056).

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failed to reach statistical significancep = 0.14not close (p > 0.1)

The difference was more marked when AFB positivity was compared between Caracas patients with SIT 17 and SIT 53, but still failed to reach statistical significance (OR = 2.44, p = 0.14).

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did not reach statistical significanceno p-value reported

In contrast, SIT 53 may be less virulent because patients with this spoligotype tended to be older and may have more AFB negative sputa, but the AFB trend did not reach statistical significance, and the older age, while reaching statistical significance, was based on only 21 SIT 53 patients and needs to be confirmed in subsequent studies.

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