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Nanoparticle-delivered multimeric soluble CD40L DNA combined with Toll-Like Receptor agonists as a treatment for melanoma.

PLoS One · 2009 · PMC2754331 · PMID 19812695

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showed a trendno p-value reported
Additionally, the triple combination showed a trend to improved survival beyond that induced by any two combinations of pSP-D-CD40L, CpG or poly(I:C), although this did not reach statistical significance in the small number of animals used in this study ( Fig. 3F , n = 5/group).

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