Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial.

Int J Med Sci · 2009 · PMC2764342 · PMID 19847319

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a strong trendno p-value reported

There was as a strong trend toward UC-II efficacy.

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did not reach statistical significanceno p-value reported

When all 20 studies were included in the meta-analysis, the results favored glucosamine with improvement in pain and functionality; however, the results were not uniformly positive and the parameters for WOMAC pain, daily function and stiffness did not reach statistical significance.

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