Age-dependent effects of low-dose nicotine treatment on cocaine-induced behavioral plasticity in rats.

Psychopharmacology (Berl) · 2009 · PMC2764852 · PMID 19727678

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a strong trendp = 0.059so close (0.05 < p ≤ 0.1)

Saline-pretreated adults showed significant locomotor sensitization, in that cocaine-induced ambulatory activity was significantly higher on day 3 than day 1; nicotine-pretreated adults showed a strong trend towards sensitization ( p = 0.059).

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a strong trend toward significancep = 0.06so close (0.05 < p ≤ 0.1)

There was a significant effect of prior cocaine exposure on cocaine-induced ambulatory activity in adult controls ( p < 0.001), and a strong trend toward significance in nicotine-pretreated adults ( p = 0.06).

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