Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes.

Diabetes · 2009 · PMC2768166 · PMID 19675135

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nominally significantno p-value reported

Although the κ values showed nominally significant heterogeneity for four of the laboratories, there was trend toward decreasing levels of κ as the elapsed time increased only for the TCP and tetramer labs.

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showed a trendno p-value reported

The ELISPOT assay utilized DR4-restricted peptides predominantly and showed a trend for greater specificity among DR4+ individuals.

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