MTHFR polymorphisms in gastric cancer and in first-degree relatives of patients with gastric cancer.

Data for men showed a trend to an increased frequency of both MTHFR 677 and 1298 variant genotypes in GC cases, while women showed a possible GC risk reduction associated with the homozygous variant MTHFR 1298CC genotype.

also in 53,322 other papers

Nonetheless, although data of MTHFR genotyping based on stratification by sex and age did not reach statistical significance in our series (Table 4 ), data are suggestive that the difference in MTHFR polymorphism association and GC risk may be partially ascribed to sex and age of recruited cases.

also in 111,027 other papers