Association of TLR4-T399I polymorphism with chronic obstructive pulmonary disease in smokers.

Clin Dev Immunol · 2009 · PMC2822240 · PMID 20169003

Europe PMC DOI

hedged sentences

0.0610

closest p · 1.2× alpha

0.0610

boldest claim

The sentences

failed to reach statistical significanceP = .061so close (0.05 < p ≤ 0.1)

Moreover, an increased frequency of the TLR4 -D299G allele in COPD was also observed but failed to reach statistical significance ( P = .061).

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did not reach statistical significanceno p-value reported

However in our study, although the presence of TLR4 -D299G polymorphism was associated with a 2-fold increased risk for COPD development, this difference did not reach statistical significance ( Table 2 ).

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