In contrast, the genes regulated by HS in PPARα-null mice overlapped with serum response factor (SRF) (one set significantly and three approaching significance) (Additional File 7 ).
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Analysis of the heat shock response in mouse liver reveals transcriptional dependence on the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha).
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The sentences
Two gene sets that approached significance were regulated by HSF1.