Nocturnal FA oxidation rate tended to be lower in HFL fed animals compared to HFP fed animals, although this failed to reach statistical significance (p = 0.08).
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High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity.
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The sentences
In parallel, hepatic expression of the insulin receptor β (IR-β), which mediates cellular insulin action, tended to be decreased in livers from mice fed stearate rich HFL and HFPS, although this did not reach statistical significance (p = 0.11 and p = 0.13 in HFL and HFPS versus HFP, respectively) (figure 3B ).