Mitogen-activated protein kinase phosphatase-1 (MKP-1) impairs the response to anti-epidermal growth factor receptor (EGFR) antibody cetuximab in metastatic colorectal cancer patients.

Br J Cancer · 2010 · PMC2853100 · PMID 20234366

Europe PMC DOI

hedged sentences

0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

showed a trendP =0.1so close (0.05 < p ≤ 0.1)

KRAS wild-type individuals with non-overexpressed MKP-1 showed a trend towards longer OS, which was not statistically significant ( P =0.1).

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did not reach statistical significanceP =0.1so close (0.05 < p ≤ 0.1)

Patients carrying KRAS-mutated tumours tended to have shorter OS, although the difference did not reach statistical significance ( P =0.1).

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