Modafinil blocks reinstatement of extinguished opiate-seeking in rats: mediation by a glutamate mechanism.

Neuropsychopharmacology · 2010 · PMC2939923 · PMID 20631691

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

Interestingly, the lower dose of modafinil (100 mg/kg), especially in combination with a higher priming dose of morphine (16 mg/kg), showed a trend toward enhancing reinstatement (although it did not reach statistical significance; Figure 1 , middle bars).

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