Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis.

Crit Care · 2010 · PMC2945131 · PMID 20682059

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

showed a trendP = 0.06so close (0.05 < p ≤ 0.1)

Patients in the TXA group showed a trend for prolonged need of mechanical ventilation (45.4 h ± 187.3 versus 25.6 h ± 128.0; P = 0.06.

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a strong trendno p-value reported

Discussion The two major findings of our study are as follows: first, in the overall cardiac surgery population studied, the administration of high-dose TXA showed a strong trend toward an association with convulsive seizures, whereas aprotinin was associated with a higher rate of stroke and neurologic disability after cardiac surgery with CPB.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.