Patterns of responding differentiate intravenous nicotine self-administration from responding for a visual stimulus in C57BL/6J mice.

6 ), a strong trend toward a main effect of session was found on the number of responses on the active lever (repeated-measures ANOVA, F 9,45 = 2.03, p = 0.06), while the number of presses on the inactive lever and the selectivity for the active lever remained stable over time.

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1a and 5 ), but the difference between the numbers of infusions earned for the same nicotine doses (i.e., 0, 0.01, 0.06, and 0.1 mg/kg/infusion) under the two different FRs did not reach statistical significance.

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