Although this difference did not reach statistical significance, our data suggest that there might be a link between pro-atherogenic stimuli and vascular profilin-1 expression.
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Profilin-1 is expressed in human atherosclerotic plaques and induces atherogenic effects on vascular smooth muscle cells.
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The sentences
As shown in Figure 5 , there was a clear trend towards increased levels of profilin-1 expression in animals that received high fat diet and subsequently developed atherosclerosis.