Barely Significant
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Local expression of tumor necrosis factor-receptor 1:immunoglobulin G can induce salivary gland dysfunction in a murine model of Sjögren's syndrome.

Arthritis Res Ther · 2009 · PMC3003528 · PMID 20003451

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showed a trendno p-value reported
Additionally, phenotyping of the infiltrating lymphocytes showed a trend to increased positive cell counts for plasma cells, CD4+ and CD8+ T lymphocytes in TNFR1:IgG treated SGs.

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There was perhaps a minor trend towards increased levels of anti-SSB (Figure 5B ) and ANA (Figure 5C ), which did not reach statistical significance.

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