A comparison of the cytokine expression in affected (acute and discoid lesion) and non-affected skin samples showed a trend towards higher cytokine overexpression in affected skin samples.
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IL-2, IL-5, TNF-α and IFN-γ mRNA expression in epidermal keratinocytes of systemic lupus erythematosus skin lesions.
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The sentences
There was no correlation between SLEDAI and cytokine expression but there was a clear trend for cytokine overexpression in samples from patients with extensive skin involvement.