Patterns of mRNA and protein expression during minus-lens compensation and recovery in tree shrew sclera.

The treated versus control eye fold difference for the proteins is shown followed by NS if the difference did not reach statistical significance (p>0.05, paired t -test).

also in 111,027 other papers

A potentially important point to be taken from the directional changes, that were highly significant by sign test while many of the individual gene expression changes were not statistically significant, is that numerous small changes in gene expression may combine to produce a larger effect.

also in 132,142 other papers

There was an overall trend toward higher expression levels in the treated eyes relative to control eyes ( Figure 2 ) after 1 day of lens wear that transitioned to selective bidirectional modulation after 4 days that suggests that there is selective regulation of the mRNA levels during the most rapid axial elongation phase with the highest scleral creep rate.

also in 4,871 other papers

The yoked downregulation in both the treated and control eyes, which is not apparent in the differential data that showed a trend toward higher levels in the treated eyes after 1 day of –5D lens and lower levels after 1 day of recovery, clouds the issue of how one should interpret a difference between the treated and control eye.

also in 53,322 other papers