hSOD1 G93A rats develop enhanced pain hypersensitivity after PSNL In comparison with WT rats, hSOD1 G93A animals showed enhanced thermal hypersensitivity following PSNL, while the increase in mechanical hypersensitivity was only mild and did not reach statistical significance.
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Enhanced neuroinflammation and pain hypersensitivity after peripheral nerve injury in rats expressing mutated superoxide dismutase 1.
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This difference was statistically significant for transgenic animals ( p < 0.001) and showed a trend towards statistical significance for WT animals (Figure 3E ).