The diurnal fat oxidation rate tended to be higher in DIO mice, but this failed to reach statistical significance ( Figure 3(e) ).
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Pharmacological modulation of dopamine receptor D2-mediated transmission alters the metabolic phenotype of diet induced obese and diet resistant C57Bl6 mice.
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Two weeks of bromocriptine treatment tended to induce weight loss in DIO mice (primarily fat mass, Figure 1(b) ), although the effect did not reach statistical significance.