Alzheimer's disease genes are associated with measures of cognitive ageing in the lothian birth cohorts of 1921 and 1936.

Int J Alzheimers Dis · 2011 · PMC3132531 · PMID 21766012

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approached significanceno p-value reported

Although not a direct replication of the result observed in the LBC1936 cohort, two BIN1 - APP interactions approached significance in the LBC1921 cohort.

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approaching significanceno p-value reported

Although the BIN1-APP interaction was not replicated in the LBC1921, an association approaching significance was observed with variants from APP and BIN1 and verbal declarative memory in the overall LBC1921 cohort.

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