Evidence for the potent anti-inflammatory effects of dexamethasone was obtained from laboratory studies; patient clinical evaluation pointed to a beneficial effect of steroid prophylaxis on the postoperative outcome which however did not reach statistical significance.
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Dexamethasone prophylaxis in pediatric open heart surgery is associated with increased blood long pentraxin PTX3: potential clinical implications.
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The sentences
These results showed a trend towards, but did not reach, statistical significance possibly due to the limited sample analyzed.