a marked trendp = 0.052
However, a total of six SNPs (rs4894559, rs1001793, rs3924519, rs11779484, rs4460370 and rs9314261) showed nominally significant association in different genetics models, and rs4872077 showed a marked trend under a recessive model (p = 0.052) as shown in Table 1 , hence, these seven SNPs could not be completely dismissed.