Reduction of long-term disability in inflammatory polyarthritis by early and persistent suppression of joint inflammation: results from the Norfolk Arthritis Register.

Analyzing both cohorts together, a significant trend toward the higher protective effect for the more stringent criterion was found (score test for trend of odds P < 0.0001).

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As a matter of fact, stratifying our analyses by DMARD treatment over the first 5 years, earlier remission showed a trend of association with better functional outcome in the subset of patients treated during the followup.

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