Brain-derived neurotrophic factor expression predicts adverse pathological & clinical outcomes in human breast cancer.

Cancer Cell Int · 2011 · PMC3156720 · PMID 21767406

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

approached significancep = 0.055so close (0.05 < p ≤ 0.1)

BDNF emerged as an independent prognostic variable in multivariate analysis for disease free survival (DFS) (p = 0.026) and approached significance for OS (p = 0.055).

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fell short of significancep = 0.055so close (0.05 < p ≤ 0.1)

The independent prognostic utility of BDNF in multivariate analysis was statistically significant for DFS (p = 0.026) and narrowly fell short of significance for OS (p = 0.055) (Table 3 ).

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did not reach statistical significanceno p-value reported

Although both absolute and normalised BDNF transcript levels were found to increase with tumour grade, this did not reach statistical significance (Figure 5 ).

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