Impact of CD1d deficiency on metabolism.

An insulin tolerance test (ITT, Figure 4D ) and pyruvate tolerance test (PTT, Figure 4E ) demonstrated a consistently strong trend to reduced insulin sensitivity in CD1d −/− mice, although these tests did not reach statistical significance.

also in 111,027 other papers

A small trend towards increased Fgf21 expression was noted, however, in fasted mice, ad libitum fed mice, and ad libitum fed LPS-injected mice.

also in 722 other papers

Fasting plasma glucose and insulin measured at the start of glucose tolerance testing (GTT) did not differ between genotypes ( Figure 4C ), although there was a strong trend for increased fasting plasma insulin concentrations in CD1d −/− mice, consistent with a trend to increased insulin resistance.

also in 5,725 other papers