A clear trend toward a dose-dependent increment of gCl was also observed in diaphragm as gCl was 1446 ± 86 μS/cm 2 ( N / n = 5/43); 1524 ± 82 μS/cm 2 ( N / n = 4/40); 1632 ± 125 μS/cm 2 ( N / n = 3/19) in vehicle, 1 mg/kg and 5 mg/kg enalapril-treated, respectively.
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Enalapril treatment discloses an early role of angiotensin II in inflammation- and oxidative stress-related muscle damage in dystrophic mdx mice.
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The sentences
This was corroborated by the observation that centronucleated fibers in enalapril-treated GC muscle also showed a trend toward smaller area, while the opposite was observed in normal fibers ( Table 2 ).