Correspondingly, the cumulative meta-analysis for comparison of the loss of function variants with stent thrombosis showed a trend of decreasing strength of association as information accumulated.
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Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: systematic review and meta-analysis.
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The sentences
This nominally significant odds ratio was subject to considerable bias across the studies (small study effect bias and replication diversity).