Survival outcomes and effect of early vs. deferred cART among HIV-infected patients diagnosed at the time of an AIDS-defining event: a cohort analysis.

Similarly, in our study, patients with PCP who deferred treatment were 90% more likely to progress to a new AIDS event or die than those initiating treatment in the first 30 days after diagnosis, although the difference between the two groups did not reach statistical significance (p = 0.09 in the adjusted analysis).

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A post-hoc analysis of the ACTG A5164 study showed a trend towards a better outcome for patients presenting with PCP starting cART in the early treatment arm, although statistical significance was not reached (p>0.05).

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