BRAF mutations in advanced cancers: clinical characteristics and outcomes.

PLoS One · 2011 · PMC3198456 · PMID 22039425

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

showed a trendp = 0.053so close (0.05 < p ≤ 0.1)

Patients younger than 60 years showed a trend towards higher likelihood of BRAF mutations (OR = 1.88, 95% CI: 0.99–3.70, p = 0.053).

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did not reach statistical significanceno p-value reported

However, in disease specific analyses, in colorectal and papillary thyroid cancer, the proportion of patients with a disease-free interval from diagnosis to metastases of over two years was less for patients with mutBRAF disease, but this did not reach statistical significance because of the small number of patients in each subgroup (data not shown).

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