Furthermore, dosing with CsA showed a trend toward reducing the accumulation of the inflammatory chemokine IL-8 in the serum of dosed pigs after 6 or 9 h, and this reduction reached statistical significance after 24 h of dosing (P < 0.05, Figure 2 B).
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Oxazolone-induced delayed type hypersensitivity reaction in the adult yucatan pigs. A useful model for drug development and validation.
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The sentences
Notably, this activity did not reach statistical significance after 6 or 24 h, but the inhibition was significant after 9 h of dosing (P < 0.05, Figure 2 B).