Comparison of two devices and two breathing patterns for exhaled breath condensate sampling.

Within the same device, hyperventilation yielded higher volumes of EBC than tidal breathing: Using the RTube we obtained 2.11 ml±0.07 ml with hyperventilation and 1.51 ml±0.09 ml with tidal breathing ( p <0.0001; figure 1a , white bars) and using the ECoScreen we obtained 1.37 ml±0.12 ml with hyperventilation and 1.05 ml±0.09 ml with tidal breathing although this difference did not reach statistical significance ( p = 0.056; figure 1a , grey bars).

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The ECoScreen showed a trend towards higher total protein amounts.

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