Because of the sibling wild-type FVB tumors, the comparison of the number of tumors between wild-type and Brk transgenic animals did not reach statistical significance ( P = 0.13).
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Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK.
2
0.1300
0.1300
The sentences
Notably, mammary tumors were infrequent events, but developed in multiparous WAP-Brk mice at a three-fold higher incidence relative to wild-type mice (Table 1 ); this trend failed to reach statistical significance.