Glucocorticoid signaling in the arcuate nucleus modulates hepatic insulin sensitivity.

After 90-min dexamethasone retrodialysis into the ARC, all three groups showed a clear trend of EGP decline, as seen in experiments 1 and 2, and this decrease reached significance in the sham denervation group ( Fig. 3 B ).

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All groups showed a trend of decreasing EGP during the intracerebroventricular and retrodialysis coadministration, but no significance was found compared with the basal level.

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