The Brugada syndrome mutation A39V does not affect surface expression of neuronal rat Cav1.2 channels.

Mol Brain · 2012 · PMC3307476 · PMID 22385640

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did not reach statistical significanceno p-value reported

Cavβ1b was able to significantly increase the surface pool of WT-Cav1.2-HA (10145 +/-790 ALUs, p = < 0.05 ANOVA), and there was a strong trend towards increased surface expression of A39V-Cav1.2 (10109 +/-842 ALUs), however, this effect did not reach statistical significance (also see Additional file 2 : Figure S2).

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