Induction of protective CD4+ T cell-mediated immunity by a Leishmania peptide delivered in recombinant influenza viruses.

PLoS One · 2012 · PMC3310046 · PMID 22470440

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did not reach statistical significanceno p-value reported

Even so, while priming led to a substantial decrease in parasite burden, differences in lesion scores did not reach statistical significance.

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a clear trendno p-value reported

The analysis of cytokine profile following SLA stimulation indicates a clear trend towards elevated levels of detrimental Th2-type cytokines in non-immunised controls, which can be linked to the lack of protection.

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