Analysis of IL12B gene variants in inflammatory bowel disease.

PLoS One · 2012 · PMC3316707 · PMID 22479607

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

showed a trendp = 0.053so close (0.05 < p ≤ 0.1)

did not reach statistical significanceno p-value reported

A haplotype of all four investigated SNPs (rs3212227-rs17860508-rs10045431-rs6887695) showed a trend for association with CD (p = 0.053); however, this potential association signal did not reach statistical significance and was uncorrected for multiple testing.

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borderline significanceno p-value reported

However, considering our limited sample size and the borderline significance of this interaction, which was lost after Bonferroni correction, this potential gene-gene interaction needs further analysis in very large cohorts or GWAS meta-analyses.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.